Tottenham will look to claim all three points from their clash with Hull to avoid slipping further off the pace of the early-season Premier League front-runners.
Mauricio Pochettino's side, who currently occupy fifth place with 27 points from 15 games, suffered just their second defeat of the 2016/17 campaign in the 1-0 reverse to Manchester United.
After losing 2-1 to league leaders Chelsea in November, Spurs seemingly got their season back on track with a 5-0 thrashing of Swansea, that was aided by the 3-1 hammering of CSKA Moscow in the Champions League.
And after putting in a good performance last time out, it took a solitary mistake for United to seal the result.
The Tigers, meanwhile, come into this game ruing two dropped points after drawing 3-3 with Crystal Palace.
It would have been their first victory since overcoming Southampton 2-1 in November, but as it is, Mike Phelan's men have recorded just three wins this term, leaving them second from bottom on 12 points – just one better than Sunderland at the foot of the table.
Pochettino admitted his team were punished by United for a mistake in defence, but aims to put that right against Hull.
"We always try to play and we build very well from the back, but then we made a mistake [for the goal], but that is football," he said.
"It's about mistakes and sometimes you're right in your decisions but we cannot change anything now.
"We created some good opportunities and the team always believed. We fought until the end to try and score but we couldn't find it. Now it is about looking forward to the next game."
Speaking ahead of the match, Phelan told the club's official website: "I thought our performance on Saturday (against Palace) was excellent. Unfortunately, a lack of concentration cost us two points.
"The team performed the way I wanted them to. We went with a slightly different system and we managed to keep the ball much better.
"In the end, we were unfortunate not to come away with a win and the three points. It's all about the next game now though. The next game is always the most important and we know that we have a tough challenge ahead of us at Spurs.
"Spurs are a top quality team looking to win things this season, but we have to try to build on what we did at the weekend."
In team news, the hosts will be without Mousa Dembele (foot), while Vincent Janssen (ankle) and Erik Lamela (hip) remain sidelined.
The visitors are missing Abel Hernandez (hernia), Will Keane (ACL knee), Moses Odubajo (patella), Greg Luer (knee) and Alex Bruce (Achilles).