Paris Saint-Germain have confirmed that the influential Angel Di Maria, Javier Pastore and Adrien Rabiot will be unavailable for Sunday's tough away trip in Ligue One to in-form Olympique Lyonnais.
Lyon are unbeaten in their last five matches, during which time they have picked up four victories and one draw.
Bruno Genesio's side have recovered momentum after a difficult run of form during September and October, and they are now amongst the chasing pack behind Monaco, Nice and PSG at the top of the table.
Runners-up for the last two seasons in the league and consistently producing exciting players from their academy, Lyon have long loomed as the Parisians most likely domestic rivals.
With that said, they may fancy their chances this weekend as Di Maria, Pastore and Rabiot have all been ruled out. The two Argentina internationals are out injured while the France midfielder has been rested by coach Unai Emery. Layvin Kurzawa is also out.